Author Guideline

Article Types

All types of articles submitted to SIM do not have any limitation on the text words, number of tables and figures, and references. All submissions need to include an abstract with 250-350 words if the word limitation was not specified in following introduction.


Original Articles are scientific reports of the results of original clinical research.

Special Articles are scientific reports of original research in such areas as economic policy, ethics, law, and health care delivery.


Brief Reports usually describe one to three patients or a single family. They begin with a brief summary of 150-250 words.

Clinical Problem-Solving manuscripts consider the step-by-step process of clinical decision making. Information about a patient is presented to an expert clinician or clinicians in stages (indicated by boldface type in the manuscript) to simulate the way such information emerges in clinical practice. The clinician responds (in regular type) as new information is presented, sharing his or her reasoning with the reader.


We welcome solicited or unsolicited review articles. All review articles undergo the same peer-review and editorial process as original research reports.

Conflicts of Interest for Review Article: Because the essence of review articles is selection and interpretation of the literature, SIM expects that the authors of such articles will not have significant financial associations with a company (or its competitor) that makes a product discussed in the article.

Clinical Practice articles are evidence-based reviews of topics relevant to practicing physicians, both primary care providers and specialists. Articles in this series should include the following sections: the clinical problem, strategies and evidence, areas of uncertainty, guidelines from professional societies, and the authors’ conclusions and recommendations. These articles should include an abstract with 200-300 words.

Other Review Articles cover a wide variety of clinical and mechanistic areas. These articles should include an abstract with 250-350 words.


Editorials usually provide commentary and analysis concerning an article in the issue of SIM in which they appear.

Perspective articles are brief, accessible pieces covering a wide variety of timely topics of relevance to health care and medicine. We welcome submissions and proposals.

Sounding Board articles are opinion essays. They are similar to editorials but are not tied to a particular article. They often present opinions on health policy issues and are normally unsolicited.

Clinical Implications of Basic Research articles discuss single papers from preclinical journals. The purpose is to explain the findings and comment on their possible clinical applications.

Special Reports are miscellaneous articles of special interest to the medical community.

Health Law, Ethics, and Human Rights are nearly always solicited, but we are willing to consider unsolicited manuscripts or proposals for manuscripts. Please send us a Presubmission Inquiry before submitting a manuscript.

Health Policy Reports are nearly always solicited, but we are willing to consider unsolicited manuscripts or proposals for manuscripts. Please send us a Presubmission Inquiry before submitting a manuscript.

Medicine and Society articles cover a range of social aspects of medicine and health care, including medical sociology, anthropology, history, and ethics, among other areas. We welcome submissions and proposals.

Letters to the Editor provide a forum for readers to comment about articles recently published in SIM, and they are a place to publish concise articles, such as reports of novel cases.

Images in Clinical Medicine are classic images of common medical conditions. Images are an important part of much of what we do and learn in medicine. This feature is intended to capture the sense of visual discovery and variety that physicians experience.

Filler Photographs are unsolicited photographs, unrelated to the content of SIM, that are published as space allows. There are no restrictions on subject matter, however photographs of recognizable people are not generally published.


  • Photo files must be submitted in JPEG format and have a file extension of .jpg or .jpeg.
  • Photos must be 1000 x 1000 pixels minimum to be considered for publication. To be eligible to be printed at the largest size, images should be 1730 pixels wide by 2000 pixels high or larger.
  • Photo files may be up to 10 MB in size.
  • A maximum of five photos may be uploaded per session.

After submitting a photo you will be notified by email once it has been reviewed by our editors. You will also receive email notification if your photo is selected for publication.


Science Insights Medicine will publish work across a broad scope of medical disciplines, including:

  • Anesthesiology
  • Cardiovascular
  • Complementary and alternative medicine
  • Critical care and emergency medicine
  • Dermatology
  • Endocrinology
  • Epidemiology
  • Gastroenterology and Hepatology
  • Genetics
  • Geriatrics
  • Hematology
  • Immunology
  • Infectious diseases
  • Mental health
  • Metabolic disorders
  • Nephrology
  • Neurology
  • Nutrition
  • Obstetrics and gynecology
  • Oncology
  • Ophthalmology
  • Oral medicine
  • Otorhinolaryngology
  • Pediatrics
  • Public Health
  • Pulmonology
  • Radiology
  • Rheumatology
  • Sports and exercise medicine
  • Surgery
  • Toxicology
  • Urology

Necessary Files

Manuscript. A single word processing file, including title, authors, abstract, main text, references and figure legends.

Figure(s). Optional

Table(s). Optional


As defined by the World Association of Medical Editors (

Plagiarism is the use of others' published and unpublished ideas or words (or other intellectual property) without attribution or permission, and presenting them as new and original rather than derived from an existing source. The intent and effect of plagiarism is to mislead the reader as to the contributions of the plagiarizer. This applies whether the ideas or words are taken from abstracts, research grant applications, Institutional Review Board applications, or unpublished or published manuscripts in any publication format (print or electronic).

Science Insights Medicine is a member iThenticate. iThenticate is a plagiarism screening service that verifies the originality of content submitted before publication. iThenticate checks submissions against millions of published research papers, and billions of web content. Authors, researchers and freelancers can also use iThenticate to screen their work before submission by visiting

Plagiarism is scientific misconduct and will be addressed as such. When plagiarism is detected at any time before publication, the Science Insights Medicine editorial office will take appropriate action as directed by the standards set forth by the Committee on Publication Ethics (COPE).

Ethical Experimentation

The report of any research involving human beings or experimental subjects must be accompanied by a statement to be included in the Additional Information section of the submission process, indicating the mechanism used for reviewing the ethics of the research conducted.

Non-native Speakers of English

Authors who are not native speakers of English who submit manuscripts to international journals often receive negative comments from referees or editors about the English-language usage in their manuscripts, and these problems can contribute to a decision to reject a paper. To help reduce the possibility of such problems, we strongly encourage such authors to take at least one of the following steps: Have your manuscript reviewed for clarity by a colleague whose native language is English.

Statistical Analysis

For manuscripts that report statistics, the Editor requires that the authors provide evidence of statistical consultation (or at least expertise) by either the inclusion of a statistician/epidemiologist among the authors, or in the acknowledgements; a biostatistician may review such manuscripts during the review process.

In the Methods section:

  • Identify the statistical tests used to analyze the data.
  • Indicate the prospectively determined P value that was taken to indicate a significant difference.
  • Cite only textbook and published article references to support your choices of tests.
  • Identify any statistics software used. (List software name, version, and company in parentheses in the text, not in the reference list.)

In the Results section:

  • Note that following the American Medical Association style manual (AMA Manual of Style: A Guide for Authors and Editors, 10th Edition. New York: Oxford University Press; 2007, page 889), the Journal does not use a zero to the left of the decimal point, because “…statistically it is not possible to prove or disprove the null hypothesis completely when only a sample of the population is tested (P cannot equal 0 or 1, except by rounding).”
  • Report actual P values rather than thresholds: not just whether the P value was above or below the significant-difference threshold. Example: write “P = .18”, not “P > .05” or “P = NS.”
  • P should be expressed to 2 digits for P ≥ .01, because expressing P to more than 3 digits does not add useful information. If P < .001, it should be expressed as P < .001, rather than P < .0001 or P = .00001 for example. In certain types of studies, it may be important to express P valuesto more significant digits. Please consult the AMA Manual of Style for further direction.
  • If P > .99, P = .999 for example, it should be expressed as P > .99.

Abbreviations, Nomenclature and Symbols

Abbreviations, nomenclature and symbols should conform to those found in the AMA Manual of Style. The use of standard international units is encouraged. Abbreviations should be used sparingly and should be spelled out the first time they are used. A list of abbreviations should be included as part of the manuscript following the title page.

Statement of Non-duplication

During the Additional Information section of the submission process, all authors must certify that their manuscript is a unique submission and is not being considered for publication by any other source in any medium. Further, the manuscript has not been published, in part or in full, in any form. Work published or presented as an abstract at a professional meeting will be considered.


All figures submitted must be owned solely by the author(s). For Figures not meeting this requirement, authors must obtain permission for the use of the figure by SIM. Obtaining this permission is the sole responsibility of the author(s). Credit must be included in the figure legend for all figures being printed with permission.

These requirements apply to the following materials:

  • Previously published materials such as figures and adapted tables or direct quotations of more than 50 words; these require permission from copyright holder (usually the original publisher).
  • Unpublished data (ie, from a personal conversation or a manuscript in preparation); these require permission from the appropriate investigator.
  • Photographs revealing unmasked faces; these require permission from the subject(s) of the photograph.

Product Information

Medications, materials, and devices must be identified by full nonproprietary name as well as brand name if appropriate and the manufacturer's name. Place this information in parentheses in the text, not in a footnote.


Science Insights Medicine adheres to the Authorship Requirements as defined by the International Committee of Medical Journal Editors (ICMJE). For more information, please visit

Everyone who is listed as an author should have made a substantial, direct, intellectual contribution to the work. For example (in the case of a research report) they should have contributed to the conception, design, analysis and/or interpretation of data.

  • Honorary or guest authorship is not acceptable.
  • Acquisition of funding and provision of technical services, patients, or materials, while they may be essential to the work, are not in themselves sufficient contributions to justify authorship.
  • Changes to Authorship that occur between revisions or prior to publication, BUT this is not allowed in SIM even this is really the truth in some cases.

Reporting Guidelines and Article Types

Reporting Guidelines

Science Insights Medicine clinical article types are based upon key reporting guidelines, as defined by the EQUATOR Network. Authors should prepare their manuscripts in accordance with the appropriate guidelines(s) and/or checklist(s) for each type of article.

The appropriate checklist (and flow diagram, if applicable) must be included with each submission.

For further information regarding reporting guidelines, authors should consult the EQUATOR Network web site (, which maintains a useful, up-to-date list of guidelines as they are published, with links to articles and checklists.


Clinical Trial/Experimental Study (CONSORT Compliant)

Reports of randomized trials must conform to the revised CONSORT guidelines and should be submitted with their protocols and a completed CONSORT checklist. All reports of clinical trials must include a summary of previous research findings and explain how the submitted trial affects this summary of previous findings. Cluster randomized trials should be reported according to extended CONSORT guidelines. Randomized trials reporting harms must be described according to extended CONSORT guidelines. All reports of randomized trials should include a section entitled “Randomization and masking” within the methods section. For information regarding CONSORT guidelines, please visit

Observational Study (STROBE Compliant)*

Observational research comprises several study designs and many topic areas. The STROBE statement should be used when reporting such research. The STROBE recommendations apply to the three main analytical designs used in observational research: cohort, case-control, and cross-sectional studies. The STROBE statement consists of a 22-item checklist. For information regarding STROBE guidelines, please visit

Systematic Review and Meta-Analysis (PRISMA Compliant)

Systematic reviews and meta-analyses must be reported according to PRISMA guidelines, an evidence-based minimum set of items created to help authors improve the reporting of systematic reviews and meta-analyses. The PRISMA Statement consists of a 27-item checklist and a four-phase flow diagram. For information regarding PRISMA guidelines, please visit

Meta-Analysis of Observational Studies in Epidemiology (MOOSE Compliant)

Systematic reviews and meta-analyses of observational studies in epidemiology should be reported according to MOOSE guidelines. For more information regarding MOOSE guidelines, please visit

Diagnostic Accuracy Study (STARD Compliant)

Investigators reporting studies of diagnostic accuracy should adhere to the STARD statement, part of the STARD initiative to improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in a study (internal validity) and to evaluate a study’s generalizability (external validity). The STARD statement consists of a 25-item checklist and recommends the use of a flow diagram to describe the design of the study and the flow of patients. For information regarding STARD guidelines, please visit

Quality Improvement Study (SQUIRE Compliant)*

The SQUIRE statement helps authors write excellent, usable articles about quality improvement in health care so that findings may be easily discovered and widely disseminated. The SQUIRE statement consists of a 19-item checklist. The SQUIRE guidelines are not exclusive of other guidelines. For example, an improvement project or effectiveness study that used a randomized controlled trial design should consider using both the CONSORT and the SQUIRE guidelines. In these cases, both checklists should be uploaded as a single document. For more information regarding SQUIRE guidelines, please visit

Economic Evaluation Study (CHEERS Compliant)

Developed by the ISPOR Quality Improvement in Cost-Effectiveness Research Task Force, the CHEERS statement supports the quality, consistency, and transparency of health economic and outcomes research reporting in the biomedical literature. The CHEERS statement includes a 24-item checklist. For more information regarding CHEERS guidelines, please visit

Clinical Case Report (CARE Compliant)

The CARE guidelines provide a framework to support the need for completeness, transparency and data analysis in case reports and data from the point of care. The main tools of CARE are the CARE Statement, CARE checklist, and a Case Report Writing Template. These products offer a rationale and a standardized format for authors to prepare more complete and transparent case reports. For more information regarding CARE guidelines, please visit